Fig 5. An immunohistochemical analysis of HEC1A (□) and HEC108 (Δ) human endometrial cancer tumors in model mice treated with PD-0332991.
The Ki-67 index was lower in the PD-0332991-treated group than in other groups. Furthermore, the PD-0332991-treated group had higher Rb expression and lower phospho-Rb expression than the control group.