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. 2017 Feb 17;11(3):409–416. doi: 10.5009/gnl16001

Table 3.

Predictive Factors for Recurrence

Variable Univariate analysis Multivariate analysis


HR 95% CI p-value HR 95% CI p-value
Age (>60 yr) 0.595 0.290–1.222 0.157
Male sex 0.502 0.234–1.073 0.075
HBV 2.053 0.712–5.922 0.183
HCV 2.328 0.680–7.969 0.178
Liver cirrhosis 1.188 0.458–3.083 0.723
MELD score (>10) 0.556 0.133–2.326 0.422
CTP score (A/B, C) 1.127 0.551–2.306 0.743
AFP (>20 ng/mL) 2.544 1.285–5.036 0.007 2.220 1.098–4.488 0.026
Tumor size (>5 cm) 1.167 0.452–3.015 0.750
Nodularity (multinodular) 5.487 2.725–11.047 <0.001 5.143 2.532–10.444 <0.001
Portal vein thrombosis 1.335 0.319–5.588 0.693

HR, hazard ratio; CI, confidence interval; HBV, hepatitis B virus; HCV, hepatitis C virus; MELD, model for end-stage liver disease; CTP, Child-Turcotte-Pugh; AFP, α-fetoprotein.