Table 4.
Predictive Factors for Survival
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age (>60 yr) | 1.282 | 0.903–1.819 | 0.164 | |||
| Male sex | 1.023 | 0.702–1.492 | 0.904 | |||
| HBV | 1.169 | 0.728–1.877 | 0.518 | |||
| HCV | 1.420 | 0.954–2.113 | 0.084 | |||
| Liver cirrhosis | 0.827 | 0.549–1.245 | 0.362 | |||
| MELD score (>10) | 1.388 | 0.821–2.345 | 0.221 | |||
| CTP score (A/B, C) | 1.606 | 1.130–2.283 | 0.008 | 1.616 | 1.116–2.339 | 0.011 |
| AFP (>20 ng/mL) | 2.277 | 1.569–3.306 | <0.001 | 1.801 | 1.215–2.668 | 0.003 |
| Tumor size (>5 cm) | 1.770 | 1.234–2.539 | 0.002 | 1.618 | 1.093–2.394 | 0.016 |
| Nodularity (multinodular) | 1.747 | 1.216–2.510 | 0.003 | 1.468 | 1.011–2.130 | 0.044 |
| Portal vein thrombosis | 2.893 | 1.872–4.470 | <0.001 | 2.389 | 1.534–3.721 | <0.001 |
HR, hazard ratio; CI, confidence interval; HBV, hepatitis B virus; HCV, hepatitis C virus; MELD, model for end-stage liver disease; CTP, Child-Turcotte-Pugh; AFP, α-fetoprotein.