Fig. 4.
Statistical evaluation of proteins with significant log2(fold changes) >1 or <−1 upon Mal or Pan IAV infection. A, B, Volcano plot analyses were used to display the changes in protein abundance at early and late time points post infection with Mal (A) and Pan (B) virus, respectively, in comparison to the 0 h time point: differences between L/H ratio of two samples were plotted against -log(p value); blue: log2(fold change) <1 or >−1, p value<0.05; red: log2(fold change) >1 or <−1, p value<0.05; t test, n = 2. C, Classification of proteins with significant log2(fold change) >1 or <−1 upon infection with Pan or Mal virus according to their gene ontology terms “biological process” (GOBP) using PANTHER (Protein analysis through evolutionary relationships) Classification System Version 10.0.