Table I. Differentially regulated proteins in Pan vs. Mal infected A549 cells. Listed are proteins with significant differences upon infection with Pan and Mal virus at indicated time points calculated by volcano plot analysis (log2(fold change) >1 or < −1, p value <0.05; t-test, n = 2). Values represent log2(L/H ratio) of the samples, (+) indicates p value <0.05.
Gene names | 4 h p.i. |
8 h p.i. |
16 h p.i. |
24 h p.i. |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Pan | Mal | sign. | Pan | Mal | sign. | Pan | Mal | sign. | Pan | Mal | sign. | |
ASPSCR1 | 1.054 | 1.517 | 0.725 | 0.810 | −0.118 | 0.979 | −0.041 | 1.135 | + | |||
CHTOP | −0.035 | −0.054 | 0.035 | 0.025 | −1.311 | −0.310 | −1.266 | −0.169 | + | |||
CRKL | 0.513 | 0.794 | 0.280 | 1.069 | 0.741 | 1.602 | 0.350 | 1.582 | + | |||
CYP1B1 | −0.207 | −0.574 | −0.400 | −0.380 | −0.223 | −0.442 | −0.527 | −1.769 | + | |||
GRB2 | 0.221 | 0.381 | −0.214 | 0.437 | −0.794 | 0.674 | −0.678 | 0.729 | + | |||
HERC2 | 0.151 | −0.870 | + | −0.623 | −0.345 | −0.742 | −0.608 | −0.620 | −0.850 | |||
KIAA0101 | 0.522 | 0.064 | −0.821 | −0.526 | −2.082 | NaN | −2.614 | −1.366 | + | |||
MUC5AC | −1.313 | −1.524 | −1.138 | −1.066 | −1.756 | −0.411 | −1.509 | −0.481 | + | |||
NRCAM | −0.688 | −0.506 | −1.047 | −2.062 | + | −2.624 | −3.085 | −3.031 | −2.502 | |||
POLDIP3 | −0.095 | 0.102 | −0.138 | −0.106 | −1.437 | 0.083 | + | −2.934 | −0.139 | + | ||
RSL1D1 | −0.042 | 0.029 | 0.155 | 0.055 | −0.428 | 0.261 | −0.989 | 0.095 | + | |||
TMBIM6 | −0.201 | 0.214 | −0.118 | 0.165 | −0.845 | 0.324 | −1.732 | −0.012 | + | |||
TRAF2 | 0.120 | 0.680 | −1.191 | 0.658 | + | −0.794 | NaN | −0.101 | NaN | |||
TRIM47 | 0.628 | 0.704 | −0.276 | 0.545 | −1.385 | 0.001 | −1.805 | 0.248 | + | |||
USP36 | −0.506 | −0.358 | −0.475 | 0.308 | −0.666 | −0.514 | −1.787 | −0.357 | + | |||
VPRBP | −0.013 | −0.397 | 0.003 | −0.545 | −0.181 | −1.284 | −0.493 | −2.149 | + |