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. 2017 Apr 24;25(5):1062–1064. doi: 10.1016/j.ymthe.2017.04.009

Figure 1.

Figure 1

In Vivo Excision of Latent HIV

(A) HIV infection, establishment of latency in humanized BLT mouse, and delivery of sgRNA saCas9 through AAV. (B) Endonuclease viral genome excision and provirus disruption leading to reduction in reservoir.