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. 2017 Mar 17;292(18):7519–7530. doi: 10.1074/jbc.M116.773960

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Figure 11. — Dex or Bet treatment antagonizes DEM-induced cytoprotection against oxidative stress. Hepa1c1c7 cells were pretreated with DEM and/or Dex (A) and DEM and/or Bet (B) for 10 h and exposed to increasing concentrations of menadione. DMSO was used as vehicle. Cell viability was analyzed after 24 h. The number of cells without menadione was set as 100%. *, p < 0.05; **, p < 0.01; ***, p < 0.001 for the comparison of DEM-treated cells with DEM + Dex-co-treated (A) and DEM + Bet-co-treated (B) cells. One-way ANOVA and Tukey's post hoc test were performed. Error bars, S.D.