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Nuclear localization of NRF2 is not affected by Dex. A, confocal microscopy analysis showing subcellular localization of NRF2 in Hepa1c1c7 cells treated with DEM and DEM + Dex. The nuclear staining by DAPI is shown in blue, and the endogenous NRF2 localization detected by anti-NRF2 antibody is shown in green. B and C, immunoblotting analysis of NRF2. Nuclear extracts of Hepa1c1c7 cells (B) and mouse livers (C) were analyzed. Lamin B was detected as a nuclear loading control.
