Figure 8.

Dex treatment reduces CBP recruitment and H3K27 acetylation at AREs. A and B, ChIP assay with anti-CBP (A) and anti-H3K27Ac (B) antibodies using Hepa1c1c7 cells treated with DEM and DEM + Dex. -Fold changes of relative enrichments for DEM + Dex-treated and vehicle-treated cells against DEM-treated cells were calculated. The average and S.D. (error bars) of the -fold changes from triplicate reactions are shown. Confidence interval estimation was conducted for DEM + Dex-treated samples. *, α < 0.05; **, α < 0.01; ns, nonsignificant.