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. 2017 Mar 3;292(18):7662–7674. doi: 10.1074/jbc.M117.775114

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© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 8. — A hypothetical model of CDPK3- and SCE1-dependent egress. The yellow lightning bolt represents stimulation with A23187 or BIPPO. Arrows represent downstream events, including direct and indirect phosphorylation events, where the thickness of the line represents the hypothetical strength of the signal. A, model of CDPK3/SCE1-dependent egress in wild-type parasites. B, egress upon loss of CDPK3. C, egress upon deletion of both CDPK3 and SCE1. D, suppression of egress upon complementation of with the SCE1 phospho-null mutant. E, egress upon complementation of an SCE1 phosphomimetic mutant.