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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Mol Cancer Ther. 2017 Feb 6;16(5):793–804. doi: 10.1158/1535-7163.MCT-16-0677

Figure 2. Derivation and analysis of acquired ganetespib resistant (GR) cells from parental A549, H460 and H358 cell lines.

Figure 2

(A) A549-GR100, H460-GR10, and H358-GR10 cells were exposed to ganetespib and cell viability was assessed by MTS assay after 72 hours in comparison to their respective parental control cells (denoted by C) (Left). Cell viability were also assessed 48 hours after treating the same three pairs of cells with 17-AAG (middle) and AT13387 (right). (B) Durability of ganetespib resistance was confirmed by long term colony formation assay in A549-GR100, H460-GR10, and H358-GR10 cells growing the cell lines in ganetespib at the indicated doses for 3 days and staining on day 10.

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