Table 3.

Unadjusted and Adjusted Analyses Comparing the Association Between PR Interval ≥230 ms Versus PR Interval <230 ms and Outcomes in Analyses Stratified by Device Type

	ICD						CRT-D						P_interaction^*
	Unadjusted			Adjusted by IPW			Unadjusted			Adjusted by IPW
	HR or sHR	95% CI	P Value	HR or sHR	95% CI	P Value	HR or sHR	95% CI	P Value	HR or sHR	95% CI	P Value
Heart failure hospitalization or death^†	1.242 (1.134–1.360)		<0.0001	1.079 (0.968–1.201)		0.1692	1.423 (1.344–1.506)		<0.0001	1.225 (1.141–1.314)		<0.0001	0.043
Death^†	1.290 (1.164–1.429)		<0.0001	1.059 (0.938–1.195)		0.3547	1.377 (1.279–1.481)		<0.0001	1.120 (1.025–1.224)		0.012	0.4437
Heart failure hospitalization^‡	1.264 (1.116–1.431)		0.0002	1.127 (0.978–1.299)		0.0987	1.413 (1.316–1.517)		0.0019	1.279 (1.180–1.387)		<0.0001	0.118

CI indicates confidence interval; CRT-D, cardiac resynchronization therapy with defibrillator; HR, hazard ratio; ICD, implantable cardioverter defibrillator; IPW, inverse probability weighted; and sHR, subdistribution hazard ratio.

For device type (CRT-D versus ICD), PR interval (≥230 ms versus <230ms), and outcome.

^†

Hazard ratio.

^‡

Subdistribution hazard ratio.