Figure 4.

Overview of SDE metabolites (BH adjusted P < 0.05) which exhibited a graded response to CR and correlations with physiological parameters (Pearson's correlations adjusted P ≤ 0.05). (A) Sphingolipids and their relationship with parameters involved in hunger signalling. (B) Sphingolipids and L‐carnitine and the relationship with markers of oxidative stress and antioxidants. (C) L‐carnitine and its precursor L‐methionine and the relationship with physiological parameters, hormones and oxidative stress markers. FAA = food anticipatory activity, MUPs = major urinary proteins, SOD = superoxide dismutase, dROMs = derivatives of reactive oxygen metabolites. Connections between metabolites and other measures indicate correlations, where red equals a positive and blue a negative correlation.