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. 2017 Mar 14;16(3):469–479. doi: 10.1111/acel.12583

Figure 2.

Figure 2

Increased incidence of CMHs is associated with gait dysfunction in hypertensive IGF‐1‐deficient mice. Regularity index (A), body speed (B), stride length (C), and base of support (front paws; D) in control mice and IGF‐1‐deficient mice under baseline conditions and after induction of CMHs. (E) Circular scatter plot showing the distribution of interlimb coupling values (phase dispersion) in control mice and IGF‐1‐deficient mice under baseline conditions and after induction of CMHs (note that the circular plot shows a smaller phase dispersion scatter in the inner circle [before hypertension] as compared to the phase dispersion scatter in the outer circle [assessed after hypertension]). Right panels shows average deviation of phase dispersion (calculated between the right hind paw [RH] and left hind paw [LH]) from the expected value (50%) under baseline conditions and after induction of CMHs. Data are mean ± SEM.*P < 0.05 vs. control baseline, & P < 0.05 vs. IGF‐1‐deficient baseline, # P < 0.05 control vs. IGF‐1 deficient (one‐way ANOVA, Tukey's post hoc test) HT: hypertension.