Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Incidence of repolarization abnormalities in the population of models under different levels of IKr block, following changes to extracellular potassium and intracellular calcium concentrations. (A) Control conditions ([K+]o = 5.4 mM, 1 Hz pacing). (B) Reduced extracellular potassium concentration ([K+]o = 4.0 mM). (C) Rapid pacing (2.5 Hz) to increase Ca2+ loading, followed by sudden decrease to 1 Hz.
