Table 3. Multivariate analysis of risk factors for lymph node involvement.
| Variable | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | ||||||
| Odds ratio | P | Odds ratio | P | Odds ratio | P | |||
| Tumor size (1 cm increase) | 1.223 (0.716–2.008) | 0.461 | 1.007 (0.564–1.797) | 0.982 | 0.941 (0.505–1.754) | 0.849 | ||
| Elevated CEA (vs. normal) | 2.093 (0.858–5.108) | 0.105 | 1.781 (0.706–4.492) | 0.222 | 2.124 (0.799–5.644) | 0.131 | ||
| Central location (vs. peripheral) | 6.409 (1.813–22.649) | 0.004 | 5.784 (1.584–21.114) | 0.008 | 7.946 (1.657–38.106) | 0.010 | ||
| Solid nodule type (vs. GGO) | 8.354 (1.074–64.995) | 0.043 | 4.575 (0.550–38.059) | 0.159 | 3.804 (0.443–32.641) | 0.223 | ||
| Visceral pleural invasion (vs. absent) | 3.378 (1.542–7.399) | 0.002 | 3.044 (1.369–6.769) | 0.006 | 2.840 (1.246–6.476) | 0.013 | ||
| Tumor SUVmax (1 unite increase) | – | 1.147 (1.035-1.272) | 0.009 | 1.249 (1.119–1.394) | <0.001 | |||
| Micropapillary and solid patterns (vs. absent) | – | – | 1.949 (0.780–4.872) | 0.153 | ||||
SUVmax, the maximum standardized uptake value; GGO, ground-glass opacity.