Fig. 4.

Application of pair correlation to expected barriers in cells. a A line is scanned across the border of two neighbor cells. b, c Intensity and pCF(7) carpets. The pCF(7) analysis highlights the presence of the impenetrable gap. The corresponding plot (right) does not yield a maximum of correlation in the gap (even at very long times). Scale bar 5 μm. d Here a line is scanned across the NE. e, f Intensity and pCF(11) carpets. The pCF(11) analysis highlights the presence of delayed communication across the NE. From the average pCF(11), two columns are extracted, 14 and 18, corresponding to regions of different cytoplasm-to-nucleus transport kinetics (i.e. passive diffusion and active import, see text). Scale bar of the image 5 μm. Figure partly taken from Cardarelli and Gratton (2010)