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. 2017 Mar 21;116(9):1141–1147. doi: 10.1038/bjc.2017.70

Table 3. Cox regression analysis and clinical scoring model for response to anti-PD-1 therapy.

Variable Odds ratio (OR) (95% CI) P value Scoring
Female 0.51 (0.27, 0.94) 0.03 1
Age <65 years 0.55 (0.30, 0.98) 0.04 1
Previous ipilimumab treatment 0.38 (0.20, 0.69) <0.001 2
Elevated LDHa 0.48 (0.25, 0.90) 0.02 1
Liver metastasis 0.34 (0.17, 0.66) <0.001 2

Abbreviations: CI=confidence interval; LDH=lactate dehydrogenase.

a

Defined as LDH ratio >1.