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. 2017 Mar 20;151(2):219–226. doi: 10.1111/imm.12725

Figure 1.

Figure 1

Proportion of regulatory T (Treg) cells and cytotoxic T lymphocyte‐associated antigen 4 (CTLA‐4)‐expressing T cells were increased in patients with chronic obstructive pulmonary disease (COPD). Circulating frequency of (a) Treg cells (as % of CD4+ T cells), (b) intracellular CTLA‐4+ Treg cells, (c) intracellular CTLA‐4+ CD4+ T cells, (d) surface CTLA‐4+ Treg cells, (e), surface CTLA‐4+ CD4+ T cells, and (f) surface CTLA‐4+ CD8+ T cells. **P < 0·01; *P < 0·05, Mann‐Whitney U‐test. The graphs show the interquartile range (box), median (middle line) and range (whiskers) for each group.