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. 2017 Mar 21;112(5):775–784. doi: 10.1038/ajg.2017.46

Table 2. Indications for breath testing.

Consensus statement Percentage of agreement Quality of evidence (GRADE)
1. Current small bowel culture techniques are not satisfactory for the assessment of SIBO. Agree (88.9% agree, 0% uncertain, 11.1% disagree) ⊕⊕⊙⊙
2. If culture is considered for diagnosis of SIBO, based on the current evidence, we suggest the threshold of >103 c.f.u./ml for the definition of SIBO Agree (77.8% agree, 11.1% uncertain, 11.1% disagree) ⊕⊕⊙⊙
3. We suggest breath testing in the diagnosis of small intestinal bacterial overgrowth. Agree (100% agree, 0% uncertain, 0% disagree) ⊕⊕⊕⊙
4. Until a true gold standard is established, we suggest breath testing in assessing the presence of antibiotic-responsive microbial colonization of the gastrointestinal tract. Agree (77.8% agree, 11.1% uncertain, 11.1% disagree) ⊕⊕⊕⊙
5. We suggest to evaluate for excessive methane excretion on breath test in association with clinical constipation and slowing of gastrointestinal transit. Agree (88.9% agree, 0% uncertain, 11.1% disagree) ⊕⊕⊕⊙
6. We suggest that breath testing should not be used for assessment of orocecal transit time. Agree (77.8% agree, 11.1% uncertain, 11.1% disagree) ⊕⊕⊕⊙
7. We suggest breath testing for the diagnosis of carbohydrate maldigestion syndromes. Agree (88.9% agree, 11.1% uncertain, 0% disagree) ⊕⊕⊕⊙
8. We suggest breath testing in the assessment of conditions with bloating. Agree (88.9% agree, 11.1% uncertain, 0% disagree) ⊕⊕⊙⊙