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. 2017 Mar 21;112(5):775–784. doi: 10.1038/ajg.2017.46

Table 4. Interpretation of breath testing.

Consensus statement Percentage of agreement Quality of evidence (GRADE)
1. We suggest that a rise of ≥20 p.p.m. from baseline in hydrogen during the test should be considered positive for fructose and lactose breath testing. Agree (100% agree, 0% uncertain, 0% disagree) ⊕⊕⊙⊙
2. We suggest that until better data are available, for clinical and research purposes, a rise of ≥20 p.p.m. from baseline in hydrogen by 90 min should be considered a positive test to suggest the presence of SIBO. Agree (77.8% agree, 11.1% uncertain, 11.1% disagree) ⊕⊕⊙⊙
3. We suggest that two peaks on breath test are not required for the diagnosis of SIBO. Agree (88.9% agree, 0% uncertain, 11.1% disagree) ⊕⊕⊙⊙
4. Until further data is available, we suggest that a level of ≥10 p.p.m. be considered positive for methane on a breath test. Agree (88.9% agree, 0% uncertain, 11.1% disagree) ⊕⊕⊙⊙
5. A firm position statement cannot be reached due to lack of conclusive data on the definition of abnormal methane on to be ≥3 p.p.m. Uncertain (44.4% agree, 44.4% uncertain, 11.1% disagree) ⊕⊕⊙⊙