Table 1.
Data quality indicators for children aged 0–14 years diagnosed with leukaemia between 1995–2009: by continent and country
| Calendar period | Registries (n) | Patients submitted (n) | Eligible patients (n [%]) | DCO (n [%]) | Any haematological malignancy (n [% of eligible]) |
Leukaemia |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Included in analyses (n [% of any haematological malignancy]) | Microscopically verified (n [%]) | Follow-up time (years) of alive patients* (median [IQR]) | Lymphoid leukaemia (n [%]) | Acute myeloid leukaemia (n [%]) | Unspecified and other specified leukaemia (n [%]) | ||||||||
| Africa | ·· | ·· | 373 | 223 (60%) | 1 (<1%) | 193 (87%) | 153 (79%) | 152 (99%) | 3·5 (0·5–4·7) | 111 (73%) | 33 (22%) | 9 (6%) | |
| Algerian registries | 2000–09 | 2 | 131 | 128 (98%) | 0 | 99 (77%) | 62 (63%) | 61 (98%) | 0·7 (0·2–3·0) | 37 (60%) | 20 (32%) | 5 (8%) | |
| Lesotho† | 1995–2009 | 1 | 27 | 27 (100%) | 0 | 27 (100%) | 27 (100%) | 27 (100%) | 6·6 (0·9–8·4) | 25 (93%) | 0 | 2 (7%) | |
| Libya (Benghazi) | 2003–04 | 1 | 23 | 23 (100%) | 1 (4%) | 22 (96%) | 21 (95%) | 21 (100%) | 4·9 (0·0–5·2) | 14 (67%) | 5 (24%) | 2 (10%) | |
| Tunisia (Central) | 1996–2007 | 1 | 192 | 45 (23%) | 0 | 45 (100%) | 43 (96%) | 43 (100%) | 1·7 (1·0–2·2) | 35 (81%) | 8 (19%) | 0 | |
| America (Central and South) | ·· | ·· | 5731 | 5722 (>99%) | 175 (3%) | 5488 (96%) | 5086 (93%) | 5063 (>99%) | 9·2 (7·3–11·5) | 4788 (94%) | 195 (4%) | 103 (2%) | |
| Argentina† | 2000–09 | 1 | 3671 | 3671 (100%) | 128 (3%) | 3496 (95%) | 3496 (100%) | 3496 (100%) | 6·5 (4·9–8·3) | 3496 (100%) | 0 | 0 | |
| Brazilian registries | 1996–2009 | 5 | 687 | 678 (99%) | 41 (6%) | 626 (92%) | 497 (79%) | 475 (96%) | 11·2 (9·8–13·1) | 387 (78%) | 79 (16%) | 31 (6%) | |
| Chilean registries | 1998–2008 | 2 | 116 | 116 (100%) | 0 | 116 (100%) | 96 (83%) | 96 (100%) | 9·2 (7·7–12·4) | 66 (69%) | 14 (15%) | 16 (17%) | |
| Colombia (Cali) | 1995–2009 | 1 | 383 | 383 (100%) | 0 | 382 (>99%) | 381 (>99%) | 381 (100%) | 6·8 (3·6–9·2) | 381 (100%) | 0 | 0 | |
| Ecuador (Quito) | 1995–2009 | 1 | 507 | 507 (100%) | 4 (1%) | 503 (99%) | 375 (75%) | 375 (100%) | 13·8 (11·5–17·3) | 295 (79%) | 67 (18%) | 13 (3%) | |
| Puerto Rico† | 2000–09 | 1 | 367 | 367 (100%) | 2 (1%) | 365 (99%) | 241 (66%) | 240 (>99%) | 7·4 (6·2–8·6) | 163 (68%) | 35 (15%) | 43 (18%) | |
| America (North) | ·· | ·· | 51 195 | 51 110 (>99%) | 144 (<1%) | 50 920 (>99%) | 36 970 (73%) | 36 156 (98%) | 10·7 (8·3–13·3) | 30 088 (81%) | 5894 (16%) | 988 (3%) | |
| Canada† | 1995–2009 | 13 | 5259 | 5200 (99%) | 13 (<1%) | 5186 (>99%) | 4152 (80%) | 3983 (96%) | 11·0 (8·6–13·5) | 3363 (81%) | 623 (15%) | 166 (4%) | |
| US registries | 1995–2009 | 38 | 45 936 | 45 910 (>99%) | 131 (<1%) | 45 734 (>99%) | 32 818 (72%) | 32 173 (98%) | 10·3 (8·0–13·1) | 26 725 (81%) | 5271 (16%) | 822 (3%) | |
| Asia | ·· | ·· | 17 371 | 17 176 (99%) | 74 (<1%) | 17 094 (>99%) | 12 552 (73%) | 12 309 (98%) | 9·6 (7·4–11·8) | 8553 (68%) | 3051 (24%) | 948 (8%) | |
| Chinese registries | 1995–2009 | 17 | 741 | 728 (98%) | 0 | 728 (100%) | 632 (87%) | 619 (98%) | 7·1 (6·3–8·2) | 309 (49%) | 149 (24%) | 174 (28%) | |
| Cyprus† | 2004–09 | 1 | 49 | 49 (100%) | 2 (4%) | 47 (96%) | 46 (98%) | 46 (100%) | 5·4 (5·1–5·8) | 35 (76%) | 10 (22%) | 1 (2%) | |
| India (Karunagappally) | 1995–2009 | 1 | 54 | 54 (100%) | 0 | 54 (100%) | 53 (98%) | 53 (100%) | 11·2 (7·4–14·8) | 43 (81%) | 8 (15%) | 2 (4%) | |
| Indonesia (Jakarta) | 2005–07 | 1 | 29 | 29 (100%) | 0 | 28 (97%) | 28 (100%) | 26 (93%) | ·· | 14 (50%) | 6 (21%) | 8 (29%) | |
| Israel† | 1995–2009 | 1 | 1880 | 1775 (94%) | 13 (1%) | 1759 (99%) | 1002 (57%) | 997 (>99%) | 10·3 (8·1–12·8) | 731 (73%) | 185 (18%) | 86 (9%) | |
| Japanese registries | 1995–2009 | 9 | 1729 | 1727 (>99%) | 46 (3%) | 1681 (97%) | 1441 (86%) | 1407 (98%) | 10·1 (6·2–11·3) | 969 (67%) | 414 (29%) | 58 (4%) | |
| Korea†‡ | 1995–2009 | 1 | 7569 | 7507 (99%) | 0 | 7507 (100%) | 5422 (72%) | 5279 (97%) | 11·5 (9·2–14·1) | 3583 (66%) | 1419 (26%) | 420 (8%) | |
| Malaysia (Penang) | 1995–2009 | 1 | 274 | 269 (98%) | 3 (1%) | 263 (98%) | 261 (99%) | 260 (>99%) | 9·4 (7·6–11·9) | 163 (62%) | 67 (26%) | 31 (12%) | |
| Mongolia† | 2005–09 | 1 | 47 | 42 (89%) | 0 | 41 (98%) | 41 (100%) | 31 (76%) | ·· | 25 (61%) | 8 (20%) | 8 (20%) | |
| Taiwan† | 1995–2009 | 1 | 3642 | 3642 (100%) | 0 | 3642 (100%) | 2641 (73%) | 2612 (99%) | 11·5 (9·2–14·0) | 1935 (73%) | 614 (23%) | 92 (3%) | |
| Thai registries | 1995–2009 | 3 | 537 | 537 (100%) | 6 (1%) | 531 (99%) | 469 (88%) | 463 (99%) | 10·8 (7·8–12·8) | 327 (70%) | 85 (18%) | 57 (12%) | |
| Turkey (Izmir) | 1995–2009 | 1 | 820 | 817 (>99%) | 4 (<1%) | 813 (>99%) | 516 (63%) | 516 (100%) | 9·2 (7·3–12·3) | 419 (81%) | 86 (17%) | 11 (2%) | |
| Europe | ·· | ·· | 45 127 | 44 003 (98%) | 165 (<1%) | 43 815 (>99%) | 31 797 (73%) | 31 256 (98%) | 11·0 (8·9–13·2) | 26 262 (83%) | 4856 (15%) | 679 (2%) | |
| Austria† | 1995–2009 | 2 | 1248 | 1209 (97%) | 0 | 1203 (>99%) | 826 (69%) | 823 (>99%) | 12·2 (9·5–14·4) | 681 (82%) | 122 (15%) | 23 (3%) | |
| Belarus† | 1995–2009 | 1 | 745 | 745 (100%) | 0 | 745 (100%) | 745 (100%) | 744 (>99%) | 12·6 (10·0–15·0) | 745 (100%) | 0 | 0 | |
| Belgium† | 2004–09 | 1 | 747 | 747 (100%) | 0 | 747 (100%) | 466 (62%) | 465 (>99%) | 8·0 (7·8–8·3) | 396 (85%) | 68 (15%) | 2 (<1%) | |
| Bulgaria† | 1995–2009 | 1 | 1079 | 1079 (100%) | 0 | 1079 (100%) | 714 (66%) | 678 (95%) | 13·0 (9·9–15·5) | 558 (78%) | 96 (13%) | 60 (8%) | |
| Croatia† | 1998–2009 | 1 | 651 | 651 (100%) | 0 | 651 (100%) | 446 (69%) | 446 (100%) | 9·9 (8·8–11·8) | 375 (84%) | 61 (14%) | 10 (2%) | |
| Denmark† | 1995–2009 | 1 | 695 | 695 (100%) | 0 | 695 (100%) | 680 (98%) | 660 (97%) | 10·4 (8·3–12·9) | 551 (81%) | 112 (16%) | 17 (3%) | |
| Estonia† | 1995–2008 | 1 | 160 | 160 (100%) | 1 (1%) | 159 (99%) | 99 (62%) | 99 (100%) | 11·9 (9·1–14·4) | 73 (74%) | 24 (24%) | 2 (2%) | |
| Finland† | 1995–2009 | 1 | 1007 | 1007 (100%) | 6 (1%) | 1001 (99%) | 728 (73%) | 726 (>99%) | 11·0 (8·5–13·5) | 593 (81%) | 101 (14%) | 34 (5%) | |
| France† | 1995–2009 | 1 | 10 619 | 10 032 (95%) | 0 | 10 030 (>99%) | 6875 (69%) | 6873 (>99%) | 9·4 (7·2–12·5) | 5611 (82%) | 1109 (16%) | 155 (2%) | |
| German registries | 1995–2009 | 13 | 3801 | 3781 (99%) | 96 (3%) | 3684 (97%) | 2661 (72%) | 2460 (92%) | 10·7 (8·4–13·4) | 2162 (81%) | 436 (16%) | 63 (2%) | |
| Iceland† | 1995–2009 | 1 | 36 | 36 (100%) | 0 | 36 (100%) | 36 (100%) | 36 (100%) | 10·9 (10·1–13·0) | 29 (81%) | 6 (17%) | 1 (3%) | |
| Ireland† | 1995–2009 | 1 | 817 | 797 (98%) | 2 (<1%) | 794 (>99%) | 571 (72%) | 570 (>99%) | 10·6 (8·2–13·2) | 458 (80%) | 99 (17%) | 14 (2%) | |
| Italian registries | 1995–2009 | 32 | 3955 | 3602 (91%) | 10 (<1%) | 3584 (>99%) | 2313 (65%) | 2247 (97%) | 9·7 (7·3–12·6) | 1930 (83%) | 336 (15%) | 47 (2%) | |
| Latvia† | 1995–2009 | 1 | 205 | 205 (100%) | 0 | 204 (>99%) | 196 (96%) | 194 (99%) | 13·4 (11·5–16·6) | 97 (49%) | 35 (18%) | 64 (33%) | |
| Lithuania† | 1995–2009 | 1 | 532 | 529 (99%) | 2 (<1%) | 527 (>99%) | 358 (68%) | 358 (100%) | 10·9 (9·1–13·6) | 301 (84%) | 53 (15%) | 4 (1%) | |
| Malta† | 1995–2009 | 1 | 92 | 92 (100%) | 0 | 92 (100%) | 61 (66%) | 60 (98%) | 10·8 (7·9–13·2) | 53 (87%) | 8 (13%) | 0 | |
| Netherlands† | 1995–2009 | 1 | 2860 | 2858 (>99%) | 3 (<1%) | 2855 (>99%) | 1988 (70%) | 1988 (100%) | 12·4 (10·1–15·0) | 1652 (83%) | 307 (15%) | 29 (1%) | |
| Norway† | 1995–2009 | 1 | 665 | 665 (100%) | 1 (<1%) | 664 (>99%) | 646 (97%) | 646 (100·0) | 10·8 (7·9–13·3) | 531 (82%) | 108 (17%) | 7 (1%) | |
| Poland (Wroclaw) | 1995–2009 | 1 | 205 | 205 (100%) | 0 | 203 (99%) | 120 (59%) | 120 (100%) | 10·2 (9·2–11·4) | 96 (80%) | 24 (20%) | 0 | |
| Portugal† | 1998–2009 | 4 | 872 | 855 (98%) | 0 | 854 (>99%) | 665 (78%) | 565 (85%) | 9·3 (8·2–10·9) | 511 (77%) | 134 (20%) | 20 (3%) | |
| Russia (Arkhangelsk) ‡ | 2000–09 | 1 | 60 | 60 (100%) | 1 (2%) | 59 (98%) | 59 (100%) | 59 (100%) | 10·7 (9·0–11·8) | 51 (86%) | 0 | 8 (14%) | |
| Slovakia† | 2000–07 | 1 | 426 | 423 (99%) | 6 (1%) | 417 (99%) | 284 (68%) | 284 (100%) | 9·7 (8·6–10·9) | 223 (79%) | 59 (21%) | 2 (1%) | |
| Slovenia† | 1995–2009 | 1 | 280 | 280 (100%) | 2 (1%) | 278 (99%) | 181 (65%) | 181 (100%) | 13·1 (10·9–15·2) | 147 (81%) | 33 (18%) | 1 (1%) | |
| Spanish registries | 1995–2009 | 11 | 1487 | 1479 (99%) | 9 (1%) | 1470 (99%) | 1152 (78%) | 1136 (99%) | 10·9 (8·6–13·3) | 997 (87%) | 123 (11%) | 32 (3%) | |
| Sweden† | 1995–2009 | 1 | 1162 | 1162 (100%) | 0 | 1162 (100%) | 1145 (99%) | 1145 (100%) | 11·1 (8·2–13·6) | 984 (86%) | 154 (13%) | 7 (1%) | |
| Switzerland† | 1995–2009 | 1 | 853 | 852 (>99%) | 1 (<1%) | 851 (>99%) | 813 (96%) | 812 (>99%) | 11·2 (9·2–13·2) | 684 (84%) | 119 (15%) | 10 (1%) | |
| UK† | 1995–2009 | 3 | 9868 | 9797 (99%) | 25 (<1%) | 9771 (>99%) | 6969 (71%) | 6881 (99%) | 12·5 (10·0–14·9) | 5773 (83%) | 1129 (16%) | 67 (1%) | |
| Oceania | ·· | ·· | 4218 | 4158 (99%) | 6 (<1%) | 4151 (>99%) | 3270 (79%) | 3143 (96%) | 11·2 (9·1–13·9) | 2672 (82%) | 544 (17%) | 54 (2%) | |
| Australian registries | 1995–2009 | 6 | 3537 | 3477 (98%) | 2 (<1%) | 3474 (>99%) | 2607 (75%) | 2480 (95%) | 9·7 (7·5–12·4) | 2145 (82%) | 424 (16%) | 38 (1%) | |
| New Zealand† | 1995–2009 | 1 | 681 | 681 (100%) | 4 (1%) | 677 (99%) | 663 (98%) | 663 (100%) | 12·8 (10·7–15·4) | 527 (79%) | 120 (18%) | 16 (2%) | |
| Total | ·· | 198 | 124 015 | 122 392 (99%) | 565 (<1%) | 121 661 (99%) | 89 828 (74%) | 88 079 (98%) | ·· | 72 474 (81%) | 14 573 (16%) | 2781 (3%) | |
Calendar period shows the maximum time span covered by the data. DCO=patients diagnosed from autopsy or Death Certificate Only (% of eligible patients). Microscopic verification=cytology or histology, or morphological verification unspecified (% of patients included in analyses).
*
Median follow-up of patients diagnosed during 1995–2004, and IQR.
†
National coverage—the data are derived from a population-based cancer registry (registries) covering the entire country.
‡
Korea: Republic of Korea; Russia: Russian Federation.