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Epicardial device leads can be a trigger for ventricular arrhythmia, even if they have been quiescent for many years.
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Epicardial device leads can cause ventricular arrhythmia without any obvious endocardial substrate abnormalities.
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Unusual provocation maneuvers should be considered outside of the standard ventricular pacing protocols, isoproterenol, and epinephrine. This should be guided by a careful history identifying unconventional triggers.