Table 2.

Toxicities of primary agents used to treat NTM infections (Griffith et al., 2007).

Drug	Toxicities
Clarithromycin	Nausea, vomiting, diarrhea⁎, hepatitis, many drug interactions
Ciprofloxacin/moxifloxacin	Nausea, vomiting, diarrhea⁎, headache, insomnia, tendonitis
Amikacin/tobramycin	Nephrotoxicity, ototoxicity, dizziness, vertigo, ataxia [monitor serum levels]
Rifampin/rifabutin	Orange discoloration of secretions, nausea, vomiting, hypersensitivity reaction, hepatitis, cytopenias, multiple drug interactions
Cefoxitin	Hypersensitivity, cytopenias, diarrhea⁎
Imipenem	Nausea, vomiting, diarrhea⁎, hypersensitivity, seizure, confusion, hepatitis, cytopenias
Tetracyclines	Nausea, vomiting, diarrhea⁎, photosensitivity, rash, dizziness, vertigo, pseudotumor cerebri
Sulfonamides	Nausea, vomiting, diarrhea⁎, cytopenias, hypersensitivity
Linezolid	Cytopenias, peripheral neuropathy, nausea, vomiting, diarrhea
Tigecycline	Nausea, vomiting, photosensitivity, pseudotumor cerebri, pancreatitis

(NTM, Nontuberculous mycobacteria).

^⁎including Clostridium difficile colitis.