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. 2017 May 4;12:34. doi: 10.1186/s13024-017-0178-8

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Downregulating ANP32A increases expression of synapse-related proteins. a, b Arresting ANP32A overexpression in htau mice increases the level of several synaptic proteins in hippocampal CA3, detected by Western blotting. c Arresting ANP32A overexpression in htau mice increases mRNA level of several synaptic proteins in the hippocampal CA3, detected by RT-PCR. Data were presented as mean ± SD. *, p<0.05, **, p<0.01 vs wt-siC; ^#, p<0.05; ^##, p<0.01 vs htau-siC (two-way ANOVA followed by Bonferroni’ s post hoc test)