TABLE 1.
Characteristics of Studies Analyzing Treatments for Chondral Lesions of the Kneea
| Study | Level of Evidence | Treatment | Outcome Scores | Defect Size, cm2, Range |
|---|---|---|---|---|
| Basad et al2 | 1 | MFx/ACI-2 | Lysholm | 4-10 |
| Clavé et al4 | 1 | OAT/ACI-2 | IKDC | 2.5-7.5 |
| Cole et al6 | 2 | MFx/ACI-2 | KOOS/IKDC | 1-10 |
| Crawford et al7 | 2 | MFx/ACI-2 | KOOS/IKDC | Not listed |
| Gudas et al9 | 1 | MFx/OAT | HSS | 1-4 |
| Knutsen et al14 | 1 | MFx/ACI-1 | Lysholm | 2-10 |
| Kon et al16 | 2 | MFx/ACI-2 | IKDC | >1 |
| Lim et al18 | 2 | MFx/OAT/ACI-1 | Lysholm | 1-4 |
| Saris et al24 | 1 | MFx/ACI-2 | KOOS | 1-5 |
| Saris et al25 | 1 | MFx/ACI-2 | KOOS/IKDC | >3 |
| Ulstein et al29 | 2 | MFx/OAT | Lysholm/KOOS | 2-6 |
| Zeifang et al31 | 2 | ACI-1/ACI-2 | Lysholm/IKDC | 2.5-6 |
aACI-1, first-generation autologous chondrocyte implantation; ACI-2, next-generation autologous chondrocyte implantation; HSS, Hospital for Special Surgery Knee Score; IKDC, International Knee Documentation Committee Subjective Knee Form; KOOS, Knee injury and Osteoarthritis Outcome Score; MFx, microfracture; OAT, osteochondral autograft transplantation.