Table 2.

Antibody Affinities as measured by Bia-Core with Epitope groping

	kon	koff	KD	Epitope
Antibody Fragment	M−1s−1	s−1	(nM)	Group
R4A1	6.42 × 104	2.85 × 10−4	4.4	2
R4B11	8.76 × 104	4.07 × 10−4	4.6	1
R4G2	1.19 × 104	4.54 × 10−4	38	2
R4G7	8.19 × 104	3.79 × 10−4	4.6	1
R4G8	9.23 × 104	6.3 × 10−3	68	3
R4G9	3.1 × 104	1.75 × 10−4	5.6	3
R4G10	1.39 × 104	7.46 × 10−4	54	2
R4G11	7.5 × 104	4.75 × 10−4	6.3	2
R4H11	3.75 × 104	4.17 × 10−4	11	1
R4H12	1.46 × 105	5.65 × 10−4	3.9	2
R3C4	1.16 × 104	3.86 × 10−4	33	ND
R3D4	1.75 × 104	8.98 × 10−4	5.1	1
R3F6	1.99 × 105	2.35 × 10−5	0.14	1
R3G2	8.3 × 103	5.78 × 10−4	69.7	2
R3H2	6.39 × 103	9.93 × 10−4	155.0	2
R3H6	1.74 × 104	5.61 × 10−4	32.3	2
R3H10	4.13 × 104	2.83 × 10−4	6.9	2