Table 4.
Proteins identified in the iTRAQ assay as decreased phosphorylation as effect of RA treatment (15 and 30 min)
| Name | Entry name | Accession | Ratio RA/control | ||
|---|---|---|---|---|---|
| 15 min | 30 min | ||||
| ATP-dependent DNA helicase 2 subunit 1 (70 kDa subunit) (Ku70) | KU70_HUMAN | P12956 | 0.7945 | ||
| ATP-dependent DNA helicase 2 subunit 2 (80 kDa subunit) (Ku80) | KU86_HUMAN | P13010 | 0.7280 | ||
| ATP-dependent RNA helicase A (DHX9) | DHX9_HUMAN | Q08211 | 0.8278 | 0.7545 | |
| ATP-dependent RNA helicase DDX39 | DDX39_HUMAN | O00148 | 0.8219 | ||
| Probable ATP-dependent RNA helicase DDX5 | DDX5_HUMAN | P17844 | 0.7272 | ||
| Spliceosome RNA helicase BAT1 | UAP56_HUMAN | Q13838 | 0.8312 | ||
| Nucleolar RNA helicase 2 | DDX21_HUMAN | Q9NR30 | 0.8583 | 0.7812 | |
| hnRNP U | HNRPU_HUMAN | Q00839 | 0.9095 | ||
| hnRNP U-like protein 1 | HNRL1_HUMAN | Q9BUJ2 | 0.7133 | ||
| hnRNP A2 /B11 | ROA2_HUMAN | P22626 | 0.8863 | 1.1729 | |
| 60S ribosomal protein L22 | RL22_HUMAN | P35268 | 0.7105 | ||
| Bromodomain adjacent to zinc finger domain protein 1B | BAZ1B_HUMAN | Q9UIG0 | 0.7057 | ||
| General transcription factor II-I (GTFII-I, TFII-I) | GTF2I_HUMAN | P78347 | 0.8136 | ||
| Histone H3 (1, 2, or 3) | H32_HUMAN | Q71DI3 | 0.7324 | ||
| Histone H4 | H4_HUMAN | P62805 | 0.6955 | ||
| Histone-binding protein RBBP4 | RBBP4_HUMAN | Q09028 | 0.8323 | ||
| Lamin-B1 | LMNB1_HUMAN | P20700 | 0.8128 | ||
| Non-POU domain-containing octamer-binding protein | NONO_HUMAN | Q15233 | 0.7489 | ||
| Nucleolar protein 5 (NOP5) | NOL5_HUMAN | Q9Y2 × 3 | 0.7909 | ||
| Nuclear mitotic apparatus protein 1 (NUMA1) | NUMA1_HUMAN | Q14980 | 0.7394 | ||
| SF, proline- and glutamine-rich (SFPQ) | SFPQ_HUMAN | P23246 | 0.8739 | ||
| Protein RRP5 homolog | RRP5_HUMAN | Q14690 | 0.6680 | ||
| RNA-binding protein Raly | RALY_HUMAN | Q9UKM9 | 0.8642 | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) | SMCA5_HUMAN | O60264 | 0.6833 | ||
| Tubulin α−chain (A, B, or C) | TBA1A_HUMAN | Q71U36 | 0.8116 | ||
| U5 snRNP 200 kDa helicase (U5-200KD) | U520_HUMAN | O75643 | 0.8612 | ||
| Ubiquitin | UBIQ_HUMAN | P62988 | 0.8675 | 0.8993 | |
The name, the SWISS-PROT entry name and accession, and the average values obtained for ratio RA/Control after 15 and 30 min RA treatment are shown. Only statistically significant values are shown.
1
hnRNP A2 /B1 is shown because it appears as decreased after 15 min and increased after 30 min RA treatment.