Table 2.
General characteristics of the experimental ZDF rats used for the clamp study
| Vehicle | MBX-102 (100 mg/kg) | |
|---|---|---|
| Posttreatment body weight (g) | 353.4 ± 5.4 | 351.2 ± 6.01 |
| Basal glucose concentration (mg/dl) | 183.1 ± 20.5 | 134.2 ± 8.11 |
| Clamped glucose concentration (mg/dl) | 152.2 ± 2.2 | 159.1 ± 1.11 |
| Basal insulin concentration (ng/ml) | 11.8 ± 1.1 | 4.6 ± 1.12 |
Values represent mean ± sem (n = 7 for vehicle-treated group and n = 6 for MBX-102-treated group.
1
P > 0.05;
2
P < 0.001 vs. vehicle-treated, unpaired two-tailed t test).