Table 4.
Predictors of In-Hospital Mortality Among DSS Patients: Univariable and Multivariable Logistic Regression Analysis
| Variables | DSS (46) | Unadjusted OR (95% CI); P Value | Adjusted OR (95% CI); P Value | |
|---|---|---|---|---|
| Dead (22) n (%) | Alive (24) n (%) | |||
| Age ≥24 yrsa | 19 (86.4) | 7 (29.2) | 15.4 (3.4–69.1); <.001 | 15.8 (2.1–119.0); .007 |
| Leucocytosis at presentation | 11 (50) | 5 (20.8) | 5.0 (1.3–19.0); .02 | — |
| Dyspnea at rest | 14 (63.6) | 7 (29.2) | 4.2 (1.2–14.6); .02 | 7.5 (1.1–52.1); .04 |
| ARDS | 11(50) | 3 (12.5) | 7 (1.6–30.4); .01 | — |
| Creatinine at presentation >1 mg/dL | 11 (50) | 6 (25) | 3.7 (1.0–13.1); .04 | — |
| AKIb | 13 (59.1) | 5 (20.8) | 5.5 (1.5–20.2); .008 | — |
| Metabolic acidosis | 14 (63.6) | 1 (4.2) | 40.2 (4.5–356.9); <.001 | — |
| Altered sensorium | 10 (45.4) | 3 (12.5) | 5.8 (1.3–25.4); .02 | 11.1 (1.2–102.6); .03 |
| Encephalitis | 6 (27.3) | 1 (4.2) | 8.6 (0.9–78.7); .04 | — |
| Peak AST >500 U/L | 8 (36.4) | 5 (20.8) | 5.1 (1.2–21.5); .03 | — |
| Peak ALT >500 U/L | 8 (36.4) | 4 (16.7) | 6.7 (1.5–30.1); .01 | — |
| DIC | 7 (100) | 0 | One sided; .003 | — |
| Vasopressor support | 18 (81.8) | 2 (8.3) | 49.5 (8.1–301.9); <.001 | — |
Abbreviations: AKI, acute kidney injury; ALT, alanine transaminase; ARDS, acute respiratory distress syndrome; AST, aspartate transaminase; CI, confidence interval; DIC, disseminated intravascular coagulation; DSS, dengue shock syndrome; KDIGO, Kidney Disease: Improving Global Outcomes; OR, odds ratio.
aIn accordance with the United Nations definition for youth: 15–24 years [14].
bIn accordance with the 2012 KDIGO criteria.