Skip to main content
. 2017 Feb 22;1(6):e000144. doi: 10.1136/esmoopen-2016-000144

Table 2.

Examples of oncogenes and tumour suppressor genes

Activating (oncogenes) Inactivating (tumour suppressor genes)
B-RAF Tumour protein (TP53)
Phosphoinositide 3-kinase (PI3K) isoforms Retinoblastoma associated (RB)
Rat sarcoma (RAS) Mammalian target of rapamycin (mTOR)
Epidermal growth factor receptor (EGFR) Phosphatase and tensin homolog (PTEN)
Platelet derived growth factor receptor A (PDGFRA)
Breast cancer1 (BRCA1)