Fig. 4.

Effect of gonadotropins and cumulus cells on oocyte nuclear maturation. Assessment of oocyte nuclear status after 26 h (A) or 44 h (B) of IVM in the presence or absence of cumulus cells and gonadotropins. Results are presented as the percentage of oocytes at intermediate stage after 26 h or at mature stage after 44 h. Statistical analysis was performed by ANOVA (P < 0.05). Different superscripts indicate significant differences according to Bonferroni’s post hoc tests; DO, denuded oocytes.