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LXR ligand suppresses protein degradation of LXRα in vivo. T0901317 (50 mg/kg) was ip injected into C57BL/6N (B6) mice for 6 or 24 h. Total protein was extracted from liver tissue of vehicle- or T0901317-treated mice (n = 4 per each group) and subjected to Western blotting analysis. Antibody for SREBP1 was used for positive control of LXR ligand. GAPDH, Glyceraldehyde-3-phosphate dehydrogenase.
