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. Author manuscript; available in PMC: 2018 Mar 16.
Published in final edited form as: Cell Chem Biol. 2017 Feb 23;24(3):316–325. doi: 10.1016/j.chembiol.2017.01.008

Figure 1. Proposed biosynthesis of 2 by PksCT.

Figure 1

The domain architecture of PksCT is shown above, with arrows indicating points of domain dissection. Mal indicates a unit of ACP-bound malonyl used for decarboxylative condensation prior to methylation. Necessary domains and substrates are shown above and below the reaction arrows. See also Figure S1 and Item S1.