Fig. 9.

Increased C/EBPβ mRNA Levels Are Associated with Increased 11β-HSD1 mRNA Levels in Adipose Tissue of Glucocorticoid-Treated Pomc^−/− Mice

Real-time PCR measurement of levels of mRNAs encoding 11β-HSD1, C/EBPβ, and C/EBPδ in retroperitoneal adipose tissue (A) or liver (B) of Pomc^−/− mice (black bars) or after 10 d treatment with corticosterone in their drinking water (25 μg/ml) (white bars) as described (25 66 ). Levels of mRNA are expressed relative to levels in untreated mice, arbitrarily set to 1. Data are mean ± sem; n = 4–6 per group. *, P < 0.05; **, P < 0.001.