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Previously inferred DFEs differ across studies. We rescaled the DFE in terms of the population size assumed or inferred in each study. A population size of 10,000 diploids is used to rescale the distribution of 2Ns to s for Eyre-Walker et al. (2006). For Boyko et al. (2008) and Li et al. (2010), we rescale the DFE from 2Ns to s using population sizes of 25,636 and 52,097 diploids, respectively (see Materials and Methods).
