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. 2017 Feb 27;206(1):345–361. doi: 10.1534/genetics.116.197145

Table 1. Performance of Fit∂a∂i on simulated data sets.

Demography nchr α (shape) β (scale) 0 ≤ |s| < 10−5 10−5 ≤ |s| < 10−4 10−4 ≤ |s| < 10−3 10−3 ≤ |s| < 10−2 10−2 ≤ |s|
Truea 0.184 3266b 0.182 0.096 0.146 0.219 0.357
Constant size 2596 0.180 ± 0.010 3712.2 ± 980.2 0.186 ± 0.009 0.095 ± 0.002 0.144 ± 0.006 0.213 ± 0.013 0.363 ± 0.016
24 0.185 ± 0.028 3613.1 ± 4196.7 0.182 ± 0.017 0.097 ± 0.009 0.148 ± 0.023 0.221 ± 0.043 0.353 ± 0.060
Two-fold expansion 2596 0.191 ± 0.007 2606.0 ± 410.7 0.178 ± 0.008 0.098 ± 0.002 0.152 ± 0.004 0.230 ± 0.009 0.341 ± 0.010
24 0.187 ± 0.023 3259.8 ± 2612.6 0.181 ± 0.016 0.097 ± 0.008 0.149 ± 0.019 0.223 ± 0.036 0.350 ± 0.050
LuCamp 2596 0.182 ± 0.008 3411.9 ± 558.5 0.184 ± 0.008 0.096 ± 0.001 0.145 ± 0.004 0.216 ± 0.008 0.358 ± 0.009
24 0.186 ± 0.027 3435.4 ± 3249.9 0.182 ± 0.017 0.097 ± 0.009 0.148 ± 0.022 0.222 ± 0.042 0.351 ± 0.060

95% intervals were estimated as ± 1.96 SD of 100 replicates in each simulation set. chr, chromosome.

a

Values show the true DFE used to simulate the data.

b

Here the simulation was scaled to an ancestral population size of N = 10,085 diploids.