Table 1. Performance of Fit∂a∂i on simulated data sets.
Demography | nchr | α (shape) | β (scale) | 0 ≤ |s| < 10−5 | 10−5 ≤ |s| < 10−4 | 10−4 ≤ |s| < 10−3 | 10−3 ≤ |s| < 10−2 | 10−2 ≤ |s| |
---|---|---|---|---|---|---|---|---|
Truea | — | 0.184 | 3266b | 0.182 | 0.096 | 0.146 | 0.219 | 0.357 |
Constant size | 2596 | 0.180 ± 0.010 | 3712.2 ± 980.2 | 0.186 ± 0.009 | 0.095 ± 0.002 | 0.144 ± 0.006 | 0.213 ± 0.013 | 0.363 ± 0.016 |
24 | 0.185 ± 0.028 | 3613.1 ± 4196.7 | 0.182 ± 0.017 | 0.097 ± 0.009 | 0.148 ± 0.023 | 0.221 ± 0.043 | 0.353 ± 0.060 | |
Two-fold expansion | 2596 | 0.191 ± 0.007 | 2606.0 ± 410.7 | 0.178 ± 0.008 | 0.098 ± 0.002 | 0.152 ± 0.004 | 0.230 ± 0.009 | 0.341 ± 0.010 |
24 | 0.187 ± 0.023 | 3259.8 ± 2612.6 | 0.181 ± 0.016 | 0.097 ± 0.008 | 0.149 ± 0.019 | 0.223 ± 0.036 | 0.350 ± 0.050 | |
LuCamp | 2596 | 0.182 ± 0.008 | 3411.9 ± 558.5 | 0.184 ± 0.008 | 0.096 ± 0.001 | 0.145 ± 0.004 | 0.216 ± 0.008 | 0.358 ± 0.009 |
24 | 0.186 ± 0.027 | 3435.4 ± 3249.9 | 0.182 ± 0.017 | 0.097 ± 0.009 | 0.148 ± 0.022 | 0.222 ± 0.042 | 0.351 ± 0.060 |
95% intervals were estimated as ± 1.96 SD of 100 replicates in each simulation set. chr, chromosome.
Values show the true DFE used to simulate the data.
Here the simulation was scaled to an ancestral population size of N = 10,085 diploids.