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. 2017 May 5;12(5):e0175515. doi: 10.1371/journal.pone.0175515

Table 1. Sociodemographic, clinical, and treatment characteristics of patients diagnosed with breast cancer, according to marital status, California, 2005–2012.

  All
N = 145564
Married
N = 83383
Single/Separated/
Divorced
N = 41521
Widowed
N = 20660
No. (%) No. (%) No. (%) No. (%)
Sociodemographic Characteristics



Age, years



<35 3108 (2.1) 1665 (2.0) 1429 (3.4) 14 (0.1)
35–49 32321 (22.2) 21433 (25.7) 10512 (25.3) 376 (1.8)
50–59 37273 (25.6) 23943 (28.7) 11892 (28.6) 1438 (7.0)
60–64 18697 (12.8) 11408 (13.7) 5742 (13.8) 1547 (7.5)
65–69 16677 (11.5) 9531 (11.4) 4646 (11.2) 2500 (12.1)
70–74 12682 (8.7) 6677 (8.0) 2981 (7.2) 3024 (14.6)
≥75 24806 (17.0) 8726 (10.5) 4319 (10.4) 11761 (56.9)
Race/ethnicity



Non-Hispanic white 90349 (62.1) 51715 (62.0) 24401 (58.8) 14233 (68.9)
Black 9324 (6.4) 3309 (4.0) 4627 (11.1) 1388 (6.7)
Hispanic 26103 (17.9) 15140 (18.2) 8108 (19.5) 2855 (13.8)
Asian/Pacific Islander 18374 (12.6) 12478 (15.0) 3896 (9.4) 2000 (9.7)
Other/unknown 1414 (1.0) 741 (0.9) 489 (1.2) 184 (0.9)
Neighborhood (block group) statewide SES quintile 


1st (lowest) 18450 (12.7) 8686 (10.4) 6815 (16.4) 2949 (14.3)
2nd 25289 (17.4) 13016 (15.6) 8106 (19.5) 4167 (20.2)
3rd 29720 (20.4) 16423 (19.7) 8814 (21.2) 4483 (21.7)
4th 34088 (23.4) 19988 (24.0) 9398 (22.6) 4702 (22.8)
5th (highest) 38017 (26.1) 25270 (30.3) 8388 (20.2) 4359 (21.1)
Insurance status



No insurance 24509 (16.8) 14679 (17.6) 7476 (18.0) 2354 (11.4)
Private 67632 (46.5) 43916 (52.7) 18306 (44.1) 5410 (26.2)
Medicare or Medicare+Private 18742 (12.9) 9324 (11.2) 3715 (8.9) 5703 (27.6)
Any Public/Medicaid/Military 30452 (20.9) 13063 (15.7) 10907 (26.3) 6482 (31.4)
Unknown 4229 (2.9) 2401 (2.9) 1117 (2.7) 711 (3.4)
Clinical Characteristics



AJCC Stage



I 66046 (45.4) 39638 (47.5) 17082 (41.1) 9326 (45.1)
II 48760 (33.5) 28144 (33.8) 14194 (34.2) 6422 (31.1)
III 17754 (12.2) 9756 (11.7) 5711 (13.8) 2287 (11.1)
IV 6982 (4.8) 3084 (3.7) 2729 (6.6) 1169 (5.7)
Unknown 6022 (4.1) 2761 (3.3) 1805 (4.3) 1456 (7.0)
Molecular subtype



HR+/HER2- 87989 (60.4) 50813 (60.9) 24510 (59.0) 12666 (61.3)
HR+/HER2+ 14538 (10.0) 8573 (10.3) 4379 (10.5) 1586 (7.7)
HR-/HER2+ 7274 (5.0) 4329 (5.2) 2116 (5.1) 829 (4.0)
Triple negative 15106 (10.4) 8705 (10.4) 4604 (11.1) 1797 (8.7)
Unclassified 20657 (14.2) 10963 (13.1) 5912 (14.2) 3782 (18.3)
Lymph node involvement



Negative 92823 (63.8) 53962 (64.7) 25195 (60.7) 13666 (66.1)
Positive 48757 (33.5) 27961 (33.5) 14966 (36.0) 5830 (28.2)
Unknown 3984 (2.7) 1460 (1.8) 1360 (3.3) 1164 (5.6)
Tumor Size (cm)
0.10 < tumor ≤0.50 9459 (6.5) 5863 (7.0) 2444 (5.9) 1152 (5.6)
0.50 <tumor ≤ 1.00 22449 (15.4) 13550 (16.3) 5620 (13.5) 3279 (15.9)
1.00 <tumor ≤ 2.00 48621 (33.4) 28997 (34.8) 13043 (31.4) 6581 (31.9)
2.00 <tumor ≤ 5.00 45579 (31.3) 25372 (30.4) 13711 (33.0) 6496 (31.4)
>5.00 11006 (7.6) 5474 (6.6) 3984 (9.6) 1548 (7.5)
Microinvasion 1546 (1.1) 962 (1.2) 414 (1.0) 170 (0.8)
Diffused 757 (0.5) 364 (0.4) 300 (0.7) 93 (0.5)
Unknown 6147 (4.2) 2801 (3.4) 2005 (4.8) 1341 (6.5)
Grade



Grade I 30988 (21.3) 18109 (21.7) 8218 (19.8) 4661 (22.6)
Grade II 58240 (40.0) 33593 (40.3) 16211 (39.0) 8436 (40.8)
Grade III/IV 46587 (32.0) 26937 (32.3) 14123 (34.0) 5527 (26.8)
Unknown 9749 (6.7) 4744 (5.7) 2969 (7.2) 2036 (9.9)
Histology



Ductal 111557 (76.6) 64600 (77.5) 32104 (77.3) 14853 (71.9)
Lobular 23418 (16.1) 13620 (16.3) 6262 (15.1) 3536 (17.1)
Other 10589 (7.3) 5163 (6.2) 3155 (7.6) 2271 (11.0)
Treatment



Surgery



No surgery 10368 (7.1) 4161 (5.0) 3783 (9.1) 2424 (11.7)
Breast conserving surgery 78579 (54.0) 46247 (55.5) 21609 (52.0) 10723 (51.9)
Mastectomy 56339 (38.7) 32845 (39.4) 16053 (38.7) 7441 (36.0)
Other/unknown 278 (0.2) 130 (0.2) 76 (0.2) 72 (0.3)
Chemotherapy



No 83953 (57.7) 45097 (54.1) 22580 (54.4) 16276 (78.8)
Yes 59274 (40.7) 36972 (44.3) 18265 (44.0) 4037 (19.5)
Unknown 2337 (1.6) 1314 (1.6) 676 (1.6) 347 (1.7)
Radiation therapy



No 76327 (52.4) 41365 (49.6) 22165 (53.4) 12797 (61.9)
Yes 69109 (47.5) 41978 (50.3) 19330 (46.6) 7801 (37.8)
Unknown 128 (0.1) 40 (0.0) 26 (0.1) 62 (0.3)

Abbreviations: SES = socioeconomic status; AJCC = American Joint Committee on Cancer; HR = hormone receptor; HER2 = human epidermal receptor 2