Table 3. Adjusted mortality rate ratios (MRR) and 95% confidence intervals (CIs) for total mortality associated with unmarried vs. married patients, by race/ethnicity, tumor subtype, neighborhood socioeconomic status (SES), nativity, and Asian/Pacific Islander (API) subgroups, California, 2005–2012.
| Total mortality | |||
|---|---|---|---|
| No. of deaths Unmarried | No. of deaths Married | MRRa (95%CI) Unmarried vs. Married |
|
| By Race/ethnicity | |||
| Non-Hispanic white | 8761 | 5858 | 1.31 (1.26–1.36) |
| Black | 1599 | 614 | 1.17 (1.05–1.30) |
| Hispanic | 1943 | 1750 | 1.15 (1.07–1.24) |
| Asian/Pacific Islander | 894 | 1006 | 1.29 (1.16–1.43) |
| Other/unknown | 109 | 76 | 1.06 (0.74–1.53) |
| P-heterogeneityb | <0.001 | ||
| Among APIs by ethnic group | |||
| Chinese | 167 | 227 | 1.21 (0.95–1.54) |
| Japanese | 125 | 92 | 1.33 (0.96–1.83) |
| Filipino | 305 | 321 | 1.24 (1.03–1.50) |
| Other Asian | 138 | 135 | 1.35 (1.02–1.79) |
| Korean | 52 | 68 | 1.38 (0.89–2.15) |
| South Asian | 47 | 84 | 0.84 (0.53–1.33) |
| Vietnamese | 60 | 79 | 1.03 (0.68–1.56) |
| P-heterogeneityb | 0.6183 | ||
| Among Hispanics by nativity | |||
| US-born | 948 | 727 | 1.23 (1.10–1.37) |
| Foreign-born | 995 | 1023 | 1.07 (0.97–1.18) |
| P-heterogeneity b | 0.010 | ||
| Among APIs by nativity | |||
| US-born | 168 | 128 | 1.62 (1.25–2.11) |
| Foreign-born | 722 | 876 | 1.25 (1.12–1.41) |
| P-heterogeneityb | 0.425 | ||
| By Neighborhood SES | |||
| 1st (lowest) | 2526 | 1357 | 1.22 (1.13–1.32) |
| 2nd | 2918 | 1804 | 1.26 (1.18–1.35) |
| 3rd | 2857 | 2009 | 1.33 (1.24–1.42) |
| 4th | 2751 | 2068 | 1.22 (1.14–1.30) |
| 5th (highest) | 2254 | 2066 | 1.32 (1.24–1.42) |
| P-heterogeneity b | 0.009 | ||
| By Tumor Subtype | |||
| HR+/HER2- | 5939 | 4102 | 1.32 (1.26–1.37) |
| HR+/HER2+ | 1157 | 899 | 1.18 (1.07–1.30) |
| HR-/HER2+ | 779 | 705 | 1.21 (1.07–1.35) |
| Triple negative | 1961 | 1803 | 1.16 (1.08–1.25) |
| Unclassified | 3470 | 1795 | 1.35 (1.25–1.46) |
| P-heterogeneityb | <0.0001 | ||
aEstimated from Cox proportional hazard models, stratified by stage (AJCC stage I-IV or unknown) and adjusted for: age continuous); race/ethnicity (NHW, non-Hispanic white, black, Hispanic, Asian/Pacific Islander, other/unknown); tumor subtype HR+/HER2-, HR+/HER2+, HR-/HER2, triple negative, and unclassified); first course of treatment (Y/N for surgery, radiation, hormone therapy); lymph node involvement (negative, positive, unknown); tumor size (continuous); grade (I, II, II/IV, unknown); histology (ductal, lobular, other); insurance status (no insurance, private insurance only, Medicare only/Medicare + private insurance, any public/Medicaid/military insurance, unknown); and neighborhood socioeconomic status (quintiles).
bLikelihood ratio test for interaction computed based on cross-product terms.