Fig. 2.

AMPK and Insulin Signaling in EDL Muscle from α2 and γ3 AMPK KO Mice and Corresponding WT Littermates

Phosphorylation of AMPK Thr¹⁷² (A and B) was determined in EDL muscle obtained from α2 AMPK KO (black bars), γ3 AMPK KO (striped bars), and corresponding WT (white bars) littermates. Results are mean ± sem; n = 8 for each genotype. ††, Genotype effect (P < 0.01) within treatment; **, treatment effect (P < 0.01) within WT. Akt Ser⁴⁷³ phosphorylation (C and D) was determined in α2 AMPK KO, γ3 AMPK KO, and corresponding WT (white bars) littermates. Results are mean ± sem; n = 8 for each genotype. **, Effect (P < 0.01) of treatment.