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. 2017 May 5;12(5):e0177174. doi: 10.1371/journal.pone.0177174

Table 2. Distribution of biochemical and physiological parameters in the total study population, as well as separated by group affiliation (model training sample N = 25/test sample N = 22) at baseline (columns 2–4) and follow-up (columns 6–8), given as median and bootstrapped 95% confidence interval of the median.

Total sample Model training sample Test sample p-Value Total sample Model training sample Test sample p-Value
Baseline Follow up
Age [y] 65 (63–67) 65 (61–70) 65 (63–67) .740 69 (67–71) 69 (65–73) 68 (66–71) .572
Hemoglobin [g/dl] 14.3 (14.1–14.6) 14.3 (13.6–14.8) 14.4 (14.1–14.9) .550 14.5 (13.9–14.6) 14.5 (13.7–14.7) 14.5 (13.9–15.0) .258
Cholesterol [mg/dl] 224 (214–232) 225 (204–233) 223 (201–237) .924 228 (210–241) 221 (205–232) 237 (212–252) .122
LDL/HDL Ratio 2.0 (1.8–2.5) 1.9 (1.7–2.7) 2.1 (1.8–2.7) .651 2.3 (1.9–2.6) 2.1 (1.7–2.7) 2.3 (1.9–2.7) .343
Triglycerides [mg/dl] 127 (108–136) 134 (101–146) 122 (103–139) .815 114 (93–128) 102 (92–122) 128 (90–149) .254
ASAT [U/l] 28 (27–30) 28 (24–34) 28 (27–31) .600 28 (27–30) 29 (25–32) 28 (26–30) .881
ALAT [U/L] 24 (22–25) 23 (22–25) 25 (21–29) .474 23 (20–26) 23 (19–29) 23 (20–26) .757
BUN [mg/dl] 17 (16–19) 17 (15–19) 18 (16–20) .724 19 (17–20) 18 (16–20) 19 (17–20) .282
Creatinine [mg/dl] 0.9 (0.9–1.0) 1.0 (0.9–1.0) 0.9 (0.9–1.0) .678 1.0 (0.9–1.0) 1.0 (0.9–1.0) 1.0 (0.9–1.0) .798
Folic acid [ng/ml] 10.4 (9.8–12.0) 10.4 (8.2–12.0) 10.9 (9.3–12.7) .550 17.1 (14.5–18.7) 16.9 (14.0–18.4) 18.7 (112.8–24.6) .543
25(OH)D [nMol] 54.1 (46.3–58.1) 53.4 (41.9–57.3) 55.6 (40.7–63.3) .572 71.8 (67.5–81.7) 67.7 (64.7–86.5) 74.5 (69.6–82.1) .522
MPO [ng/ml] 876.0 (740.0–1127.6) 802.9 (667.0–1292.5) 889.3 (622.1–1213.3) .798
IGF-1 [ng/ml] 137 (114–148) 119 (103–154) 140 (121–148) .436 162 (145–176) 152 (133–179) 168 (152–180) .232
Training volume [h/week] 5.0 (4.5–6.0) 5.5 (4.0–8.0) 5.0 (4.0–6.0) .352 6.5 (5.0–8.0) 8.0 (5.0–10.0) 6.0 (3.5–8.0) .138
Absolute physical performance [W] 200 (188–225) 200 (188–250) 194 (175–219) .069 200 (177–222) 220 (178–225) 187 (169–218) .112
Relative physical performance [%] 152 (144–167) 155 (144–169) 150 (129–169) .232 149 (134–156) 153 (134–164) 139 (123–159) .208

MPO was measured only at baseline. The p-values are derived from Mann-Whitney U tests assessing differences between the model training and the test sample.