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. Author manuscript; available in PMC: 2017 May 5.
Published in final edited form as: Bioorg Med Chem. 2016 Nov 12;25(5):1571–1584. doi: 10.1016/j.bmc.2016.11.019

Table 8.

Washout experiments with T. brucei.a

Compound 24H 48H 72H 96H
Pentamidine 4X 4X 1X 1X
64 32X 16X 16X 16X
69 16X 32X 16X 32X
72 16X 8X 8X 4X
79 32X 64X 64X 16X
66 128X 128X 64X 64X
a

The values indicate the concentration of compound relative to the 48-h EC50 and the duration of exposure that resulted in no outgrowth of cells after another 10 days of observation in media without compound.