Table 2.

Transcriptional Effects of the S203A Mutation

Promoter	Cell Line	Endogenous SF1 Expression	Effect on Transcription	Ref. Nos.
hCYP17	COS-1	−	Small decrease	This study
StAR	HTB9	−	Small decrease	60
αGSU	αT3–1	+	Major decrease	7
MIS	JEG3	−	Major decrease	4
CYP11A	JEG3	−	Major decrease	4
hCYP17	H295R	+	No effect	59
HDL-R	HTB9	−	No effect	60
CYP1B1	Y1	+	No effect	61

See text for details.