. Author manuscript; available in PMC: 2017 May 5.

Published in final edited form as: South Afr J HIV Med. 2012 Jun 7;13(2):87–104. doi: 10.4102/sajhivmed.v13i2.146

Table 2. Thrombocytopaenia and HIV infection.

Decreased production	Increased loss/destruction/sequestration
Drugs	Immune thrombocytopaenia (secondary – HIV associated)
AZT	Immune thrombocytopaenia (secondary – HIV associated)
Co-trimoxazole	Thrombotic thrombocytopenic purpura (TTP)
Fluconazole	Thrombotic thrombocytopenic purpura (TTP)
Ganciclovir	Disseminated intravascular coagulation (DIC)
Acyclovir	Disseminated intravascular coagulation (DIC)
Rifabutin	Haemolytic uraemic syndrome (HUS)
Clarithromycin	Hypersplenism
Didanosine	Infection
Chemotherapy	Haemophagocytosis
Deficiencies	Drugs
Vitamin B₁₂	Interferon
Folate	Saquinavir
Infections	Secondary anti-phospholipid syndrome
HIV
CMV
MTB
MAC
Histoplasma capsulatum
Neoplasia
Hodgkin’s disease
Non-Hodgkin’s lymphoma
Miscellaneous
Hypoplastic/aplastic anaemia
Haemophagocytic syndrome
Secondary myelodysplastic syndrome