Table 1.
Baseline characteristics of patients in the four groups
| Characteristics | All groups | Definite MI | Possible MI | Raised cTnT only | No cTn rise | P value* |
| Group size (n) | 172 | 21 | 51 | 73 | 27 | |
| Total number of cTnT results | 997 | 138 | 318 | 415 | 126 | |
| Median number of cTnT results per patient (min–max) | 6 (1–11) | 7 (1–11) | 6 (1–11) | 6 (1–11) | 3 (1–11) | |
| Age, mean (SD) | 63.0 (16.6) | 61.4 (14.4) | 68.6 (14.4) | 64.9 (15.2) | 48.4 (17.7) | <0.01 |
| Female sex, n (%) | 72 (42%) | 8 (38%) | 22 (43%) | 34 (47%) | 8 (30%) | 0.48 |
| White ethnicity, n (%) | 142 (83%) | 18 (86%) | 40 (80%) | 63 (90%) | 21 (84%) | 0.33 |
| APACHE II score on admission to ICU, mean (SD) | 18.2 (6.6) | 18.0 (6.22) | 18.9 (6.2) | 20.0 (6.5) | 12.5 (4.8) | <0.01 |
| Serum creatinine ≥140 μmol/L at any time during study period, n (%) | 76 (44.2%) | 10 (47.6%) | 26 (51%) | 39 (53.4%) | 1 (3.7%) | <0.001 |
| Treatment with RRT, n (%) | 54 (31.4%) | 7 (33.3%) | 16 (31.4%) | 30 (41.1%) | 1 (3.7%) | 0.005 |
| RRT or serum creatinine ≥140 μmol/L, n (%) | 87 (50.6%) | 10 (47.6%) | 31 (60.8%) | 45 (61.6%) | 1 (3.7%) | <0.001 |
| Comorbidities | ||||||
| Ischemic heart disease, n (%) | 33 (20%) | 6 (29%) | 12 (24%) | 13 (18%) | 2 (7%) | 0.23 |
| Hypertension, n (%) | 67 (39%) | 8 (38%) | 30 (59%) | 24 (33%) | 5 (19%) | <0.01 |
| Diabetes, n (%) | 51 (30%) | 8 (38%) | 20 (39%) | 20 (27%) | 3 (11%) | 0.06 |
| Any form of vascular disease, n (%) | 34 (20%) | 4 (19%) | 15 (29%) | 14 (19%) | 1 (3.7%) | 0.06 |
| Mortality | ||||||
| In hospital, n (%) | 42 (24%) | 6 (29%) | 16 (31%) | 19 (26%) | 1 (3.7%) | 0.03 |
| In ICU, n (%) | 32 (19%) | 5 (24%) | 11 (22%) | 15 (21%) | 1 (3.7%) | 0.44 |
*P values are for the test of heterogeneity among the four proportions or means as appropriate.
APACHE indicates acute physiology and chronic health; cTnT, cardiac troponin T; ICU, intensive care unit; RRT, renal replacement therapy; SD, standard deviation.