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. 2017 Apr 6;9(4):e1142. doi: 10.7759/cureus.1142

Table 1. Characteristics of the three included studies.

ALT: Alanine aminotransferase; ANP: Atrial natriuretic peptide; BMI: Body mass index; BP: Blood pressure; CAD: Coronary artery disease; COR: Crude odds ratio; ECG: Electrocardiogram; HF: Heart failure; hs-CRP: High sensitivity C- reactive protein; IHD: Ischemic heart disease; LVH: Left ventricular hypertrophy; NAFLD: Non-alcoholic fatty liver disease; VHD: Valvular heart disease.

Study Population Mean Age (NAFLD/No-NAFLD) Males % (NAFLD/No-NAFLD) NAFLD Assessment AF Assessment Outcome (AF/Total) Mean Follow-up Time Adjustment of Covariates Result
  • Karajamaki AJ, 2015

  • Finland

  • Prospective Cohort Study

Total; 958 NAFLD: 249 Non-NAFLD: 709 52±6/51±6 58/43 Hepatic ultrasonography by a radiologist with 10-year experience Based on standard 12-lead resting ECG. (noted in medical records) NAFLD: 37/249 Non-NAFLD: 56/709 16.3 years Age, sex, diabetes mellitus, BMI, waist circumference, smoking, serum ALT, systolic BP, Left atrial diameter, ANP, CAD and hs-CRP COR 1.96 (1.29-2.97)
  • Targher G, 2013

  • Italy

  • Prospective Cohort Study

Total: 400 NAFLD: 281 Non-NAFLD: 119 63±9/64±9 59.4/57.1 Hepatic ultrasonography performed in all patients by an experienced radiologist, who was blind to the participants' details   Based on a standard 12-lead resting ECG. (noted in routine examination, or in medical records)   NAFLD: 38/281 Non-NAFLD: 4/119   10 years Age, sex, hypertension, LVH status and PR interval COR 4.49 (1.6-12.9)
  • Targher G, 2013

  • Italy

  • Cross-Sectional Study

Total: 702 NAFLD: 514 Non-NAFLD: 188 65±13/68±14 55.6/49.5 Hepatic ultrasonography was performed in all patients by experienced radiologists, who were blinded to subjects' characteristics Based on a standard 12-lead ECG done during hospital stay; or from medical history. (noted during hospital stay, or in medical records) NAFLD: 75/514 Non-NAFLD: 10/188         - Age, sex, diabetes duration, HbA1c, LVH status, IHD, VHD and HF COR 3.04 (1.54-6.02)