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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Cancer Surviv. 2017 Jan 9;11(3):309–319. doi: 10.1007/s11764-016-0589-5

Table 2.

Association of emotional distress with HRQOL in both childhood cancer survivors and siblings

Anxiety Depression Somatization
Yes (N=6,765)
Mean (SD)
No (N=556)
Mean (SD)
p-value Yes (N=6,466)
Mean (SD)
No (N=856)
Mean (SD)
p-value Yes (N=6,320)
Mean (SD)
No (N=1,000)
Mean (SD)
p-value
Physical functioning 75.71 (26.03) 88.63 (19.27) <0.001 75.39 (27.15) 89.27 (18.45) <0.001 68.04 (27.94) 90.76 (16.59) <0.001
Role limitations due to physical health problems 59.35 (42.28) 84.86 (31.12) <0.001 60.62 (41.54) 85.88 (30.26) <0.001 48.79 (42.72) 88.31 (27.30) <0.001
Bodily pain 55.55 (26.25) 76.99 (22.25) <0.001 59.48 (27.28) 77.47 (21.85) <0.001 49.08 (24.04) 79.51 (20.24) <0.001
General health perceptions 48.31 (25.11) 71.46 (21.66) <0.001 50.16 (24.62) 72.31 (21.20) <0.001 43.79 (23.66) 73.79 (19.74) <0.001
Vitality 35.31 (20.75) 58.37 (20.22) <0.001 34.66 (18.90) 59.54 (19.68) <0.001 34.85 (19.94) 60.06 (19.22) <0.001
Social functioning 51.49 (27.49) 86.43 (20.04) <0.001 51.45 (25.97) 88.06 (18.34) <0.001 58.02 (28.03) 87.87 (18.68) <0.001
Role limitations due to emotional problems 37.64 (40.18) 85.15 (30.37) <0.001 38.63 (39.91) 87.22 (28.23) <0.001 54.84 (43.14) 85.79 (29.77) <0.001
Mental health 43.41 (17.84) 76.17 (15.34) <0.001 45.01 (16.54) 77.49 (14.11) <0.001 56.36 (20.95) 76.43 (15.57) <0.001

Based on t-tests

Means and standard deviations represent t-scores with a population mean = 50 and a standard deviation = 10. Higher t-scores reflect better HRQOL

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