Fig. 4.

Example gene network identified from differentially expressed genes by Ingenuity Pathway Analysis (IPA) showing differential response of p. major satellite cell transcriptome to temperature. Depicted is the top scoring skeletal and muscle system development network identified by Comparison Analysis. a) RBC2 line, 33 °C versus 38 °C. b) F line, 33 °C versus 38 °C. c). RBC2 line, 43 °C versus 38 °C. d) F line, 43 °C versus 38 °C. In each panel the direction (red = up regulated, green = down regulated) and magnitude (color intensity) of expression changes are indicate for each of the group comparisons. Gray indicates molecule that were included in the dataset but did not meet the significance cutoff value. Shapes within the networks correspond to genes, gene products, or small molecules and “Double circle” symbols indicate gene complexes or groups