Table 1.
Pre-operative clinical data: sex, age at disease onset, disease duration, anti-epileptic drugs (AEDs), epileptogenic temporal lobe (defined by EEG seizure onset), MRI, hemisphere dominance assessed by fMRI and pre-operative neuropsychological test results.
Nr/Id/Sex | Age at disease onset | Disease duration (yrs) | AED at time of investigation | Epileptogenic temp lobe (to be resected) | Hemisphere dominance by word generation fMRI | MRI pathology |
CD List recall (SD) |
CD Delayed recall (SD) |
RCFT delayed recall (SD) |
---|---|---|---|---|---|---|---|---|---|
1/M | 28 | 13 | CBZ | R TL | Left | R mesial sclerosis | -0.5 | 0.3 | -0.5 |
2/F | 17 | 18 | LTG, GBP | R TL | Not available | R occipital demarcated infarction; R hc atrophy | 0.3 | 0.5 | -2.2 |
3/M | 47 | 7 | LTG, VPA | R TL | Left | 0 | 0.5 | 0.7 | 0.7 |
4/F | 34 | 5 | LEV, CBZ, PGB | R TL | Not available | 0 | 1 | 0.6 | -1.3 |
5/F | 34 | 4 | CBZ | R TL | Not available | 0 | -0.5 | -0.2 | -2.3 |
6/F | 8 | 19 | LTG | R TL | Not available | R mesial sclerosis | -1.6 | -2.5 | -2.6 |
7/M | 15 | 32 | LEV | L TL | Not available | L TL suspect DNET | -0.7 | -1.3 | 0.5 |
8/M | 19 | 4 | VPA, LTG | L TL | Left | L TL suspect DNET | -1.4 | 0.1 | -1.9 |
9/F | 1 | 31 | LTG, CLB | L TL | Not available | L mesial sclerosis | 0.1 | -2.1 | -1.1 |
10/F | 19 | 12 | PGB, CBZ | L TL | Not available | L mesial sclerosis | -3.3 | -2.7 | --* |
11/M | 25 | 5 | OXC | L TL | Not available | L TL low-grade astrocytoma | 0.8 | -4.5 | -1.6 |
12/F | 10 | 20 | LTG, VPA | L TL | Not available | L mesial sclerosis | -0.2 | -0.1 | 0.0 |
13/F | 13 | 11 | LTG | L TL | Left | 0 | -0.8 | -0.8 | -1.2 |
14/F | 32 | 28 | LEV, OXC | L TL | Not available | L mesial sclerosis | -2.2 | -0.5 | -1.3 |
*Not able to perform CBZ Carbamazepine; LTG Lamotrigine; GBP Gabapentin; VPA Valproic Acid; LEV Levetiracetam; PGB Pregabalin; CLB Clobazam; OXC Oxcarbazepine. L Left; R Right; TL Temporal Lobe; DNET Dysembryoplastic Neuroepithelial Tumour; SD Standard Deviation; CD Claseson-Dahl Learning and Retention Test; RCFT Rey Complex Figure Test