Table 2.
Quality of life in the active surveillance (AS), radical prostatectomy (RP), radiotherapy (RT), and reference groups
| Score range | AS | RP | RT | Reference | All groups | AS vs. RP | AS vs. RT | AS vs. Ref. | RP vs. RT | |
|---|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | P value* | P value# | P value# | P value# | P value# | ||
| Generic health | ||||||||||
| SF12-PCS | 0–100 | 50.7 (6.6) | 48.4 (7.7) | 47.8 (8.3) | 48.7 (7.7) | 0.023 | 0.317 | 0.011 | 0.173 | 0.910 |
| SF12-MCS | 0–100 | 54.5 (9.4) | 52.0 (9.2) | 54.6 (8.5) | 53.1 (9.6) | 0.163 | 0.451 | 0.994 | 0.665 | 0.255 |
| Respondent’s self-reported health | ||||||||||
| EQ-VAS | 0–100 | 81.8 (12.7) | 78.6 (15.0) | 78.3 (14.1) | 79.5 (12.4) | 0.145 | 0.355 | 0.122 | 0.546 | 1.00 |
| Generic anxiety | ||||||||||
| STAI-6 | 20–80 | 31.4 (8.4) | 33.5 (10.5) | 33.2 (8.6) | 32.3 (9.4) | 0.195 | 0.508 | 0.199 | 0.862 | 1.00 |
| Highly anxious, N (%) | ≥44 | 10 (8.3%) | 9 (13.0%) | 27 (12.3%) | 24 (11.8%) | 0.746 | 0.374 | 0.327 | 0.320 | 0.903 |
| Prostate-specific health | ||||||||||
| EPIC | ||||||||||
| Urinary summary | 0–100 | 91.3 (10.0) | 85.6 (14.4) | 89.6 (14.7) | 92.1 (9.7) | 0.002 | 0.006 | 0.094 | 0.963 | 0.342 |
| Urinary function | 0–100 | 93.0 (10.6) | 80.0 (19.1) | 89.7 (16.2) | 93.3 (9.5) | <0.001 | <0.001 | 0.087 | 0.995 | <0.001 |
| Urinary bother | 0–100 | 90.0 (11.8) | 89.9 (13.1) | 89.4 (15.1) | 91.2 (12.1) | 0.889 | 0.992 | 0.977 | 0.999 | 0.920 |
| Urinary incontinence | 0–100 | 90.0 (14.6) | 70.1 (28.8) | 86.5 (20.3) | 90.4 (13.9) | <0.001 | <0.001 | 0.428 | 0.999 | <0.001 |
| Urinary irritative | 0–100 | 92.7 (8.9) | 95.5 (7.2) | 92.2 (12.6) | 93.7 (8.8) | 0.043 | 0.475 | 0.509 | 1.00 | 0.034 |
| Bowel summary | 0–100 | 96.7 (6.4) | 94.6 (8.0) | 94.7 (7.8) | 96.1 (6.9) | 0.996 | 0.997 | 1.00 | 1.00 | 0.995 |
| Bowel function | 0–100 | 95.7 (6.0) | 92.6 (9.2) | 93.0 (9.1) | 94.4 (8.5) | 0.712 | 0.929 | 0.662 | 0.793 | 0.993 |
| Bowel bother | 0–100 | 97.7 (7.7) | 96.6 (8.3) | 96.4 (7.7) | 97.8 (6.3) | 0.640 | 0.955 | 0.622 | 0.687 | 0.974 |
| Sexual summary | 0–100 | 53.9 (20.1) | 34.2 (14.9) | 41.1 (20.2) | 49.8 (20.1) | 0.008 | 0.008 ‡ | 0.228 | 0.874 | 0.221 |
| Sexual function | 0–100 | 40.9 (24.6) | 14.8 (17.7) | 25.8 (25.0) | 35.3 (24.7) | <0.001 | <0.001 ‡ | 0.069 | 0.716 | 0.045 |
| Sexual bother | 0–100 | 83.2 (23.4) | 77.8 (30.2) | 75.8 (26.7) | 83.7 (23.8) | 0.873 | 0.995 | 0.998 | 0.955 | 0.978 |
SD standard deviation
*Significance tested with ANOVA for all four groups
#ANOVA Tukey post hoc test
‡Observed difference is clinically relevant, because difference exceeds 0.5 standard deviation